Phillies vs. Yankees prediction and odds for Wednesday, April 5 (pitching probables, lineup)

Mar 30, 2023; Bronx, New York, USA; New York Yankees starting pitcher Gerrit Cole (45) follows
Mar 30, 2023; Bronx, New York, USA; New York Yankees starting pitcher Gerrit Cole (45) follows / Brad Penner-USA TODAY Sports

The Yankees and Phillies finish a three game series on Wednesday afternoon with each ace taking the mound.

Gerrit Cole was as good as advertised in his Opening Day start against the Giants, tossing six shutout innings with 11 strikeouts. Can he shut down a standout Phillies lineup and outduel ace Aaron Nola, who struggled in his first outing against the Rangers?

Nola was knocked around for five earned runs on Opening Day and will have his hands full on Wednesday against the Yankees, but can he get back on track?

Here are the odds and our best bet:

Phillies vs. Yankees odds, run line and total

Yankees Lineup for Wednesday, April 5 vs Phillies

No Giancarlo Stanton. Yes Franchy Cordero. Let's see it.

Phillies vs. Yankees prediction and pick

We'll start with Nola, who couldn't find his footing in his first start, but I won't let that cloud my judgement that this is a Cy Young level pitcher. He couldn't get out of the fourth inning, allowing five earned runs, all coming in that last inning as the Rangers broke the game wide open. However, he is a year removed from a stellar year in which he pitched a 3.25 ERA with over 200 innings of work and had a FIP of 2.58.

I believe he's in line for a bounce back outing on Wednesday afternoon, but he will not be able to match Cole's excellence, who looks ripe for a Cy Young run in 2023.

The Phillies offense is formidable, but Cole is one of the best in baseball, striking out more than 12 batters per nine innings dating back to 2018. It also helps that his biggest issue last season, limiting home runs, likely won't play a role in this one, given the chilly conditions in the Bronx on Wednesday afternoon.

It's a low total, but I expect Nola to round into form and Cole to be lights out yet again. Give me the under.

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Game odds refresh periodically and are subject to change.